Generally, you should avoid the use of frames, unless it improves the usability of your site substantially.
Accessible Frame Navigation
When disable people who use assistive technology visit a FRAMESET page, they must choose which frame to open from a list of frames on the page. You must provide meaningful frame titles, so that disable users can easily identify the frame they want to open.
To achieve this:
Accessible Frame Source
To create an accessible frame source, the source of the FRAME element should always be an HTML file.
However, if the source of a FRAME is an image file, then you can't add an alternative text (ALT) attribute. Therefore, the source of the frame is inaccessible.
The solution is to link to a HTML file, which contains an image tag with alternative text attributes.
Use the NOFRAMES tag to specify equivalent content for browsers that cannot support frames, or are configured not to display frames.
You could also use the NOFRAMES tag and link to a single Web page that combines the content of all the frames.